<I>Infection of Jaw Cysts and Lipidperoxides Content (TBA value) of Jaw Cyst Walls</I>

概要

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The average TBA value of infectioned jaw cysts fluid was higher, and polyunsaturated fatty acid relative content was lower, than those of non-infected or infection eradicated cysts fluid by irrigation with antibiotic solution. When infection was eradicated by irrigation, the average TBA value and polyunsaturated fatty acid relative content returned to the level of non-infected cysts fluid. Then the average TBA value of infected jaw cyst walls was higher than that of non-infected or infection eradicated jaw cyst walls by irrigation. Indomethacin, added to the homogenate of jaw cyst walls <I>in vitro</I>, lowered the TBA value. The magnitude of indomethacin-effect seemed to correlate positively with the original TBA value. Indomethacin inhibits fatty acid cyclooxyenase, and TBA value could be thought as an indicator of syntheses of PG-endoperoxides. And then its supposed that the syntheses of PG-endoperoxides in infected-jaw-cysts were more stimulated as compared with non-infected ones. Therefore in conclusion the TBA value of jaw cyst walls may reflect the degree of inflammation in the tissue.
日本炎症・再生医学会の論文