Changes of mast cells in the inflammatory foci

概要

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The localization and appearance of mast cells of acute and chronic inflammatory processes of the paranasal lesions in the cases of chronic sinuitis were examined pathohistologically in this paper. Mast cells were seen around and/or attached to the small blood vessels in the connective tissue. Mast cells were easily found in the acute exsudative inflammatory foci, but scarcely in the areas of lymphocytic, plasmocytic, and histiocytic infiltration of the chronic inflammatory stage. Mast cells were found scatteredly in the areas of the proliferation of collagen fibers or fibrosis. In the acute inflammatory process with neutrophilic and eosinophilic infiltration mast cells showed the degranulation and the degrees of the degranulation of mast cells varied. The mast cells were occasionally seen as the clear cells. It seems that mast cells have active behaviours in the early stage of the inflammatory processes and play an important role in fibrosis in the repair stage of the inflammatory processes human-pathohistologically.
日本炎症・再生医学会の論文