Heparin-free, low-concentration heparin and FOY-heparin hemodialysis in patients with hemorrhagic tendency

概要

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In patients with hemorrhagic tendency, we have sought for a method of hemodialysis with low-dose heparin in 141 cases since 1980. Hemodialysis was performed by the following three different methods: (a) continuous infusion of normal saline at a rate of 200ml/hr without heparin, and several additional introductions of the saline in a volume of 200ml at 30-min intervals; (b) several bolus injections of minimum doses of heparin; and (c) continuous drip infusion of heparin at a rate of 100U/hr together with infusion of FOY solution (3g/200ml saline) at a rate of 50ml/hr. With the second method, the amount of heparin in each injection was so adjusted that the clotting time was within an acceptable range. Throughout each hemodialysis, no trouble has been encountered with respect to HFAK and clot-formation within the perfusing circuit.
社団法人日本透析医学会の論文