Autoanti-Jka antibody in a patient with Sjoegren syndrome.
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概要
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A-43-year-old woman presented with thrombocytopenia and a positive direct antiglobulin test, and was found to have an antibody with anti-Jka spesificity in her serum and elute. Her red blood cells treated with chloroquine were typed as Jk(a+b+) and absorbed the antibody. And she had never had a blood transfusion, not taken any drugs. She was diagnosed as Sjögren syndrome and had no clinical or hematologic evidence of hemolytic anemia. The titration of autoantibody was 8 in her serum and 4 in her elute and was non reactive after treatment with 2-mercaptoethanol. Class and subclass of the antibody was determind as IgG1.Through the clinical course in this case, thrombocytopenia was improved without any treatments, titration of antibody was almost no change and any signs of hemolysis were not found. Autoanti-Jka antibody was not common and we were aware of only 13 previously reported examples.
- 一般社団法人 日本輸血・細胞治療学会の論文
一般社団法人 日本輸血・細胞治療学会 | 論文
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