The evaluation of Nipro's automated membrane device for plasma collection.
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概要
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Plasmapheresis using the automated membrane device (NDP-100) for plasma collection was carried out on 219 normal donors. The aim of this study was the evaluation of donor safety, the recovery rates of proteins and coagulation factors, and the efficiency of the plasma collection in Red Cross Blood Centers.As to donor safety, there were no significant changes in the donor's physical and biochemical test results. Complement activation, as already indicated, was noticed to be slightly elevated. The obtained plasma showed good protein recovery such as total protein, albumin, IgG, fibrinogen and factor VIII and IX levels. However, this procedure required around 60 minutes to collect 400ml of plasma (needle to needle time), plus 15 minutes for set-up and priming the device. As a result, an operator can only carry out four plasmaphereses a day. Furthermore, because of the long needle to needle time, many donors who experienced the centrifuge system using Haemonetics PCS did not agree to the use of NDP 100 device for the following donation.In conclusion, this system is required to shorten the time of the procedure.
- 一般社団法人 日本輸血・細胞治療学会の論文
一般社団法人 日本輸血・細胞治療学会 | 論文
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