Malignant Fibrous Histiocytoma in the Lumbar Area of a Dairy Cow.
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概要
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A tumor mass 8 cm in diameter, was noticed on the left lumbar area of a 5-year-old dairy cow and enlarged to 16 cm in diameter 5 months later. The cow calved one month later, but was euthanatized at 2 months postpartum, because of deteriorating condition with decreased milk production. Grossly, the epidermis overlying the tumor was hyperkeratotic and partially ulcerated. The tumor affected the dermis, subcutis and muscles with necrotic or hemorrhagic foci at the center, extending to the peritoneum. The left subiliac, supramammary, medial iliac and lumbar aortic lymph nodes were enlarged. Microscopy revealed that the tumor tissue consisted of dense proliferation of fibroblastoid and histiocytoid cells, partly with foamy cells or multinucleated giant cells. Erythrophagia by histiocytoid cells was observed in hemorrhagic foci. Ultrastructurally, histiocytoid cells had abundant cytoplasmic organelles, as well as desmosome-like structures between adjoining cells.
- 公益社団法人 日本獣医師会の論文
公益社団法人 日本獣医師会 | 論文
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