The Action Mechanism of Phototherapy with Emphasis on Photoimmunologic Effects.
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概要
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Recently phototherapy, including UVB and PUVA, is one of the most popular modalities for the treatment of a variety of cutaneous diseases, although the action mechanisms have not been fully understood.On the other hand, it has been clarified that the skin is an important immunologic organ whose constitutive cells are all involved in immunologic reactions.We have investigated so far the effect of PUVA and UVB radiation on the immunecompetent cells, including epidermal Langerhans cells, Tlymphocytes, mast cells and endothelial cells and also on the contact hypersensitivity.The results obtained from these experiments suggest that phototherapy exerts its anti-allergic and anti-inflammatory effects through the immunosuppressive ability.
- 日本皮膚科学会大阪地方会の論文
日本皮膚科学会大阪地方会 | 論文
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