Twelve Cases of Chronic Pyoderma and Its Variants: Analysis of the HLA Antigens ans Laboratory Data.
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概要
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We analysed the HLA antigens and immunological, bacteriological and endocrinologica data in twelve patients with chronic pyodermia and its variants. Although HLA-A, B, C and DR antigens in all patients and HLA-DQ antigens in some of them were detected and compared with the healthy Japanese controls, no defined illness-susceptable antigen was detected. Granulocyte functions (phagocytosis, oxygen production and chemotaxis) in peripheral blood from four patients were within normal level. Low levels of the dehydroepiandrosterone (DHEA), one of the major component of androgen, were detected in 3 out of 4 patients analysed. This study indicates that the disease may not be associated with a certain HLA antigen nor gra ulocyt e di sf unction. However, there is a possibillity that the endocrinic disf unction is related to the pathogenesis of the disease.
- 日本皮膚科学会大阪地方会の論文
日本皮膚科学会大阪地方会 | 論文
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