A Case of Pityriasis Rubra Pilaris-like Erupion with Erythroderma, Alopecia Universalis and Generalized Depigmentation.
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概要
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A 44-year-old male patient with severe diabetes mellitus who developed erythroderma secondary to pityriasis rubra pilaris (PRP)-like eruption was given systemic treatment with etretinate. Although the hyperkeratotic erythema gradually cleared, liver dysfunction with ascites, muscle atrophy, fatigue, alopecia universalis, generalized depigmen tation and relapsing pyoderma appeared. After etretinate therapy was discontinued, liver function gradually recovered and vellus hairs reappeared in the whole body. One year later, PRP disappeared completely and spotted or patchy pigmentations recovered.<BR>It was suggested that etretinate, PRP, severe diabetes mellitus and some abnormal immunological functions might have intereacted with resultant occurrence of these unusual clinical conditions in this case.
- 日本皮膚科学会大阪地方会の論文
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