A case of pemphigus vegetans with lesions on distal dorsum of the feet.
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概要
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A 72-year-old man developed asymptomatic lesions on his inguinal region 5 years ago. The lesions consisted of sharply demarcated, erosive and hypertrophic plaques and pustules. A biopsy specimen from the lesion showed acanthosis and acantholytis in the epidermis, and, by immunofluorescence, IgG was detected in the intercellular spaces of the epidermis. He was diagnosed as pemphigus vegetans and treated with oral steroid. Similar lesions developed on his distal dorsum of the feet 3 years later. Histopathological and immunohistopathological findings of the biopsy specimen taken from the lesion were compatible with those of pemphigus vegetans. The lesion on foot in this disease is rare and seems to be caused by physical stimulation such as shoes and walk.
- 日本皮膚科学会大阪地方会の論文
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