A case of progressive systemic scleroderma with synthesis of elastic fibers and amyloid deposition in the sclerotic dermis.
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概要
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A 56-year-old woman had an edematous sclerotic skin on the all fingers and dorsal hands, and radial furrowing around the mouth. Skin biopsy specimen was taken from the left middle finger and was examined light and electron microscopically. Light microscopy showed compact, thick collagen and fine, irregularly running elastic fibers throughout the dermis. Dylon staining disclosed amyloid deposits in the dermal papilla. Electron microscopy revealed newly synthesized elastic fibers close to or enwrapped by fibroblasts. Amyloid masses contained various amount of elastic fibers, suggestive of a close relationship between amyloid and elastic fibers.
- 日本皮膚科学会大阪地方会の論文
日本皮膚科学会大阪地方会 | 論文
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