Postnatal development of nerve fibers in rat temporomandibular joint.
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概要
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This study was designed to investigate postnatal changes in innervation in rat TMJ disk, using immunohistochemical methods with antibodies against PGP 9.5 and CGRP.Twenty-eight Wistar strain rats (0-40-day-old) were perfused through the left venticle. The tissue blocks including the temporomandibular joint were carefully removed, decalcified, and finally cut into sagittal and/or frontal serial sections. The sections were processed for the immunohistochemical staining using the labeled-streptavidin-biotin method. A few nerve fibers, which invaded near the middle area at birth, became localized in the peripheral area. In the peripheral area, the number of nerve fibers increased during the postnatal development. No special nerve terminals were observed, although varicosity-like structures regarded as the free nerve endings increased during postnatal development.It was suggested that the postnatal development of the nerve fibers in the articular disk is associated with the development of the occlusion and the joint structure.
- 一般社団法人 日本顎関節学会の論文
一般社団法人 日本顎関節学会 | 論文
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