Properties of Apatite Cement Composed of α-Tricalcium Phosphate and Tetracalcium Phosphate

概要

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Some properties of apatite cement which is composed of α-tricalcium phosphate and tetracalcium phosphate were investigated for use as a biomaterial. The setting time and some physical properties were affected by the liquid/cement (L/C) ratio, but all of these results were suitable to be used for biomaterial. The results of a fatigue test showed high dynamic strength (30Hz, 200kgf/cm2, 107 cycles). Exothermic temperature of the hydraulic hardening reaction was nearly human body temperature. In a liquid analysis, the concentration of Ca2+ was about 15 ppm and the pH elevation was over 10 at an early stage, but after that, pH fell down around neutrality in 3 days. Finally, the hydraulic hardened product had a porous body that was a good environment for new bone formation. In animal experiments they showed the excellent new bone formation and high biocompatibility.
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