Backbone Conformational Pattern Clustering of Three-Dimensional Peptide Fragments of Proteins
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概要
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In this paper we aim to examine in detail the data distribution within each conformational pattem class and to identify some local common structural features among the fragments in a particular cluster (or subcluster). Backbone conformational pattern clustering was carried out for the three-dimensional peptide fragments where the Φ-ψ, conformational pattern of the TA (target amino acid) belongs to class A (α-helix dominant class) or β(n-sheet dominant class) as defined in our previous work. The analysis for the fragments of class A suggested that these fragments involve four representative local backbone conformational patterns, not only for typical α-helix fragments but also for fragments closely related to <I>type I turn</I> or the starting moieties of α-helices. On the other hand, the analysis for class B fragments showed that these have much more diversity than class A fragments with respect to their local backbone structures. The details of the methods and results of the analyses are discussed here.
- 日本バイオインフォマティクス学会の論文
日本バイオインフォマティクス学会 | 論文
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