Histopathology of atypical vasular proliferation of pyogenic granuloma of the upper respiratory tract: Kenyan and other cases.:KENYAN AND OTHER CASES

概要

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Pyogenic granuloma (PG) is polypoid lesion of cutaneous or mucosal tissue composed of lobular capillary hemangioma. Affected sites of the lesion should be gingiva, fingers, lips, face and tongue in descending order of frequency. Not rarely ulcerous lesions accompany PG. Although cellular atypia is not remarkable, it recur occasionally when the surgical or conservative treatment is not perfect. In this work, we studied cellular atypia of endothelial cells of PG of the upper respiratory tract of Kenyan patients, and histologically compared with other vascular proliferative lesions of soft tissue such as angiosarcoma, Kaposi's sarcoma and non-specific granulation tissue. A wide variety of cellular atypia was observed. The results suggested that there could be atypical transformation of proliferative endothelial cells of PG of the upper respiratory tract of the patients in such areas as repeated infection could occur.
日本熱帯医学会の論文