A gastric adenocarcinoma case with dead Schistosoma japonicum egg deposition in the regional lymphnodes.

概要

論文の詳細を見る
A 79 years old woman with past history living in an endemic area of Schistosoma japonicum developed gastric adenocarcinoma. She lived in Yamanashi, Masuno until 19 years old, then left the place and never returned back there. The patient was subjected to a total gastrectomy with splenectomy. By histological examination, Schistosoma japonicum eggs were detected in a considerable number of lymphnodes along the lesser curvature. The eggs were also found in the splenic lymphnodes. Fibrosis with the egg deposition in the Glisson's sheath of biopsied specimen of the liver was partly observed but not very extensive. By stool examination no egg was demonstrated and the serological tests by COP and CF were negative, which supported the view that the patient did not carry alive parasite. Although any definite evidence was not raised in the present case, an etiological role of the Schistosoma japonicum eggs in the development of stomach cancer was suggested even 50 years after the infection. This kind of cases should be further studied for the clarification of carcinogenic stimulus by dead Schistosoma japonicum eggs.
日本熱帯医学会の論文