EVALUATION OF SODIUM HYALURONATE SOLUTION FOR REMOVING DRUGS IN THE MOUTH AFTER STEROID INHALATION

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概要

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• We studied the effects of mouth wash-mouth rinsing and gargling- on removing drug residues from the mouth after steroid nebulization. The concentration of fluticazone propionate in mouthwash after drug inhalation was measured by HPLC. We used sodium hyaluronate solution and water and the mouth was wet or dry. Sodium hyaluronate solution removed drugs from the mouth better than water and removal was greater under wet than dry conditions. These results indicate that sodium hyaluronate solution is useful for removing steroid nebulization residue from the mouth. Conditions in the mouth should also be noted before gargling in giving guidance to patients.

• 耳鼻咽喉科展望会の論文

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