CEFMENOXIME HYDROCHLORIDE, NEBULIZATION AND STABILITY VIA A NEW ULTRASONIC NEBULIZER
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概要
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Ultrasonic nebulization, although widely used in inhalant therapy, poses problems in drug stability in inhalant solutions during ultrasonic nebulization. We studied the effectiveness of a ultrasonic nebulizer (NE-U 22) developed by Omron, focusing on cefmenoxime hydrochloride stability. Stability tests showed drug ratios exceeding 95% after ultrasonic nebulization using the new ultrasonic nebulizer, indicating, the drug is highly stable when the new ultrasonic nebulizer is used. The nebulizer generates an aerosol that delivers particles smaller than a commpressor nebulizer and occupies less dead volume in the medicine container. We concluded that use of the new ultrasonic nebulizier offers advantages in cefmenoxime hydrochloride inhalant therapy.
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