Concervative therapy with cervical intraepitherial neoplasia and the usefulness of cytology to detect recurrence.
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概要
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<B><I>Objective</I>:</B> We evaluated the significance of HPV infection in cytology for predicting the recurrence of cervical intraepitherial neoplasia after conservative treatment.<BR><B><I>Study Design</I>:</B> Subject were 554 women treated for dysplasia in 129, CIS in 224, and stage Ia cervical cancer in 201 by hysterectomy, conization, and laser vaporization. Koilocytosis as HPV infection was examined with recurrence after treatment.<BR><B><I>Results</I>:</B> Uterus-preservation therapy using laser vaporization or conization was conducted on 94% with dysplasia, 53% with CIS, and 18% with stage Ia cervical cancer. Recurrence was as follows: dysplasia: 4/17 (24%); CIS: 1/7 (14%) in laser vaporization, and dysplasia: 4/104 (4%) and CIS: 3/113 (3%) in conization. Koilocytosis was detected cytologically or histologically in pre-or posttreatment with all recurrences.<BR><B><I>Conclusion</I>:</B> Koilocytosis as an HPV infection is a significant predictive factor for the recurrence of cervical intraepitherial neoplasia after conservative treatment.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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