Salvage Surgery Following Three-year Remission of Non-small Cell Lung Cancer with Malignant Pericardial Effusion.

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A 69-year-old man was admitted to our hospital because of massive pericardial effusion, which was diagnosed as malignant by pericardocentesis and pericardial biopsy. He underwent surgical pericardial drainage with topical installation of cytocidal drugs. Subsequent three cycles of systemic chemotherapy consisted of cisplatin, vindesine and mitomycin C resulted in partial response. The disease did not progress until the primary nodule enlarged three years later. No recurrence of lymph node metastases and pericardial effusion or emergence of other organ metastases were seen. He underwent left upper lobectomy as salvage surgery. Histologically, the tumor was diagnosed as poorly-differentiated adenocarcinoma composed of malignant cells with morphological similarity to those found in the biopsy specimen of the pericardium three years previously. No tumor cells were found in the dissected mediastinal lymph nodes and in the re-biopsied pericardium.
特定非営利活動法人日本肺癌学会の論文