Two-year Survival after Chemotherapy in Patients with Stage III B or IV Adenocarcinoma of the Lung Evaluated using Quality-adjusted Survival Analysis.
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We evaluated the characteristics of 2-year survivors among 146 patients with stage IIIB or N adenocarcinoma of the lung admitted to our hospital from 1986-1994. Twentyfive patients were survived over 2 years. Univariate prognostic factor analysis for 2-year survivors identified a good performance status as significant. Two-year survivors showed a higher response rate and underwent repeated treatments. We evaluated the effect of chemotherapy on QOL in 2-year survivors by quality-adjusted survival analysis known as a Q-TWiST (Quality adjusted Time Without Symptoms and Toxicity) analysis. If ut was nearly O, namely toxicity due to chemotherapy was severe, mean QTWiST at 2 years of follow was approximately 70% of the value when healthy.
- 特定非営利活動法人 日本肺癌学会の論文
特定非営利活動法人 日本肺癌学会 | 論文
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