Ten Cases of Primary Mediastinal Malignant Germ Cell Tumor.

概要

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Ten cases of primary mediastinal malignant germ cell tumors were studied retrospectively. All but one were male and most of the patients suffered from chest pain or cough. While 3 patients who were classified as seminoma had normal serum tumor markers, seven non-seminomas had high levels of α-fetoprotein (AFP) or carcinoembryonic antigen (CEA). Of the 5 patients who initially received cisplatin-based combination chemotherapy, 3 attained a pathological complete response (CR) by thoracotomy.<BR>Of the 5 patients whose tumors were initially resected, 4 received adjuvant cisplatincontaining chemotherapy.<BR>In summary 7 of the 9 remain alive and disease-free. These results strongly suggest that combined modality treatment provides good results for patients with primary mediastinal malignant germ cell tumor.
特定非営利活動法人日本肺癌学会の論文