A Case of Post-transfusion GVHD (Graft Versus Host Disease) Like Syndrome Following Right Lower Lobectomy for Lung Cancer.

概要

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A 71-year-old male was admitted to our hospital from another hospital, and hemosputum and an abnormal shadow on his chest X-ray were pointed out. We diagnosed the abnormal shadow with cavitation as lung cancer, and performed right lower lobectomy. 6 units of CRC and 10 units FFP were used during the operation. The postoperative course was good but he developed a high fever on the 11th day after operation.<BR>He then developed systemic erythroderma on the 13th day after operation and died on the 23rd day as a result of diarrhea, liver dysfunction, pancytopenia, sepsis and acute renal failure. Bone marrow aspiration showed hypoplastic findings. Based on the clinical picture and bone marrow biopsy, we made a diagnosis of post-transfusion GVHD-like syndrome. Use of irradiated blood is advised to prevent the occurrence of this fatal complication. This case is the first report of post-transfusion GVHD-like syndrome after lung lobectomy.
特定非営利活動法人日本肺癌学会の論文