Clinicopathological Studies of Bronchial Gland Cell Type Mucus-producing Adenocarcinoma of the Lung.:producing Adenocarcinoma of the Lung

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• Twenty-five resected cases of bronchial gland cell type adenocarcinoma of the lung were examined clinicopathologically. They were 5.6% of adenocarcinoma cases surgically resected from 1972 to 1990. The age of the 10 males and 15 females varied from 29 to 76 years: the mean age was 53.7. Twelve patients complained of cough, sputum, bloody sputum, chest pain and/or back pain. The smoking rate was 56%. There were 6 hilar type cases, occurring as far as 4th order bronchi, and the remaining 19 cases were peripheral lung cancer cases. Pathologically, there were 4 stage I cases, 2 stage II, 8 stage III A, 6 stage III B and 5 cases of stage N. Lymph node metastases were observed in 18 of 24 cases examined. There were 9 pneumonectomy cases, 1 bilobectomy, 14 lobectomies and 1 partial resection. Combined resection including resection of the pericardium, pleura, thoracic wall, superior vena cava, left atrium, esophagus and/or aorta was performed in 8 cases. Local recurrence was observed in the lung and pericardium, and distant metastases to the bone, brain and liver appeared. Each case of bronchial gland cell type adenocarcinoma was matched with 3 cases of Clara cell type and bronchial surface epithelial cell (BSE) type adenocarcinoma as to sex, age and stage. Bronchial gland cell type adenocarcinoma showed better prognosis than Clara cell and BSE type adenocarcinomas, but there was no statistical significance.<BR>Therefore, bronchial gland cell type adenocarcinoma is considered to be a clinicopathologically different type of mucus-producing adenocarcinoma from goblet cell type adenocarcinoma.

• 特定非営利活動法人 日本肺癌学会の論文

特定非営利活動法人 日本肺癌学会 | 論文

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