Craniotomy for Cure of Non-small Cell Lung Cancers with Brain Metastasis as a Single Organ Metastasis.

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• Pathological studies based upon autopsies of lung cancer patients report that not a few have brain metastasis as a single organ distant metastasis. Cure can, therefore, be expected by removing both lesions. It has been our routine to remove such a brain metastasis occurring after thoracotomy, aiming at cure. It has also been our routine approach in cases with concomitant brain and chest lesions to work closely with neurosurgeons on a schedule of a series of surgeries, to remove the brain lesion first, then to remove the primary lesion in not later than 7-10 days following the craniotomy and to give cranial radiation and systemic chemotherapy including cisplatinum.<BR>Of our 7 patients undergoing craniotomy after curative thoracotomy, two have been well and tumor-free for more than 5 years, yielding a five-year survival rate of 28.5% following craniotomy. At present there is not yet any long term survivor among our 4 patients undergoing craniotomy followed by thoracotomy. But one survived for 2 years and 4 months postoperatively with a fair quality of life. In face of reports of 5 year postoperative survival rates of 30-40% following craniotomy for cure, regardless of the time courses of the brain metastasis from the primary lesion, craniotomy along with thoracotomy for cure in patients of non-small cell lung cancer with single organ brain metastasis may be indicated in some cases even in stage N category.

• 特定非営利活動法人 日本肺癌学会の論文

特定非営利活動法人 日本肺癌学会 | 論文

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