Histopathological Study of the Lung Cancers:Special Reference to the Grade of Malignancy

概要

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Eighty four cases of lung cancers treated surgically were studied histologically with special reference to the blood vessel invasion and prognosis after surgery.<BR>The incidnce of blood vessel invasion for the entire cases was 63 percent, while it was 83 percent for epidermoid carcinomas and 47 percent for adenocarcinomas. According to the classification of Japan Lung Cancer Society'(New Classification) blood vessel invasion was found 36 percent for well differentiated cases in frequency, 64 percent for moderately differentiated cases, and 88 percent for poorly differentiated cases respectively.<BR>Correlation with blood vessel invasion and prognosis after surgery was studied for 41 cases, whose post-operative course was followed exactly. The cases without blood vessel invasion survived 83 percent more than 3 years, while the cases with it survived only 21 percent more than 3 years and about 70 percent of those patients died within 2 years.<BR>Connective tissue of the lung cancers was divided into three types, type I;abundant in fibroblasts, type Thiess fibroblasts and large numbers of collagen fibers, type IIl;almost collagen fibers and it may be show tendency of hyalin degenenation. The patients who had lung cancers with type II, or III showed poor prognosis after surgery.
特定非営利活動法人日本肺癌学会の論文