Tumor Doubling Time and PPD Skin Test Reactivity in Resectable Lung Cancer

概要

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The relationship between tumor size, tumor doubling time (tD) and PPD skin test reactivity (PPD) was studied in 132 patients with resectable lung cancer which included various histological type of bronchogenic carcinoma. Serial x-ray films showed following tD; adenocarcinoma had an average doubling time of 116 days, squamous cell carcinoma of 94 days and large and small cell carcinoma of 71 days. TD was getting shorter with increased pathological stage.<BR>There was no relationship between tumor size and tD in any type of carcinoma, however, it was strongly suggested that there was a certain relationship between these parameters if studies were carried out in those patients who had strong or weak PPD and who had a small size tumor less than 30mm on chest x-ray film.<BR>These observations indicate that immunotherapy is important as an adjuvant after resection of the lesions in lung cancer patients.
特定非営利活動法人日本肺癌学会の論文