Clinical study of parathyroid function in end-stage renal failure

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Aims: To investigate hyperplasia of the parathyroid glands in end-stage renal failure, 31 predialysis patients were examined.Results: Hyperplasia of a parathyroid gland (φ5-10mm) was detected in only 5 patients by ultrasonography. There was no correlation between the serum parathyroid hormone level and hyperplasia of the parathyroid gland. However, there was a significant correlation between the serum corrected calcium level, sex and hyperplasia of the parathyroid gland.Conclusion: We suggest that severe renal osteodystrophy is limited in end-stage renal failure. However, parathyroid gland hyperplasia developed in 5/31 (16.1%) patients. We concluded that management of secondary hyperparathyroidism should be started early during the course of chronic renal failure.
社団法人日本透析医学会の論文