A clinical study of six rhabdomyolysis cases.

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We conducted a study of six rhabdomyolysis (RML) cases encountered at our center during the 3-year period from 1988 through 1990. The patients were all males and ranged in age from 32 to 67 years (mean age: 45±12 years). The cause of RML was external trauma in 3 cases. The other 3 cases had no history of external trauma. All cases were complicated by renal failure, 1 patient suffered an acute aggravation of chronic renal failure, and the other 5 had acute renal failure.Two patients improved with conservative treatment, but the other 4 required blood purification (hemodialysis: HD and/or hemodiafiltration: HDF). Although the elimination rate of serum myoglobin (Mb) during blood purification was only 6.3% on HD, it ranged from 22.2-50.0% on HDF with a mean rate of 31.9%.Four of the six patients svrvived. The courses of the two patients who died were complicated by multiple organ failure (MOF).
社団法人日本透析医学会の論文