A case of ventricular tachycardia induced by antiarrhythmic drugs during hemodialysis.

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A case of ventricular tachycardia induced by antiarrhythmic drugs during hemodialysis is reported. The patient was a 56-year-old woman who was initiated on regular dialysis because of chronic renal failure at the age of 49. At 56 years of age, she suffered from dyspnea related to inadequate dialysis. One week after admission, she experienced a syncopal attack due to ventricular tachycardia induced by an antiarrhythmic drug. Two months later, she also experienced a syncopal attack due to ventricular tachycardia induced by pilsicainide. DC shock was required on both occasions. Recently, the provocation of serious arrhythmias by antiarrhythmic drugs has been recognized. This phenomenon is termed "proarrhythmia". However, to our knowledge, no reports have appeared of proarrhythmia during hemodialysis. When antiarrythmic agents are used, serum drug concentrations should be carefully monitored at regular intervals.
社団法人日本透析医学会の論文