Clinical studies on the anemia due to blood donation. II

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• Hematological studies were carried out serially on the blood donors.When 400ml, of blood were withdrawn each month from healthy males with supposedly normal iron stores, the reduction in the serum iron concentration became manifest within five to six months.Decrease of the hemoglobin concentration and of packed red cell volume followed approximately one month later. Red cell counts were only slightly reduced or unchanged, and the anemia was hypochromic and microcytic in type.In females or subjects with supposedly depleted iron stores, the anemia became more manifest in shorter periods after repeated donations than normal adult males.The significance of the storage iron in the development of the anemia was discussed.

• 一般社団法人 日本輸血・細胞治療学会の論文

一般社団法人 日本輸血・細胞治療学会 | 論文

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