<I>Changes in leukocytes in peritoneal exudates and blood and vascular permeability of mice after glycogen administration</I>
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概要
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Kinetics of inflammatory cell accumulation in mice in response to glycogen and influence of protease inhibitors and anti-inflammatory drugs were studied. Leukocytes in blood maximally increased at 2 hr after glycogen injection. The maximum cell accumulation in the peritoneal cavity was observed at 8 hr, whereas the protein content in the peritoneal exudate reached the maximum level at 1-2 hr and then decreased. Among drugs examined, indomethacin and dexamethasone suppressed markedly the accumulation of white cells and protein exudation.
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