<I>Studies of Anticomplementary and Antiinflammatory Effects of L-cysteine as one of Sulfhydryl-Compounds</I>
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概要
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Sulfhydryl-and thiol-compounds are very important and active in biological activities. L-cysteine is simple and the most fundamental amino acid.<BR>The effects of it in proteinogram, various serum proteins and complements were studied before and after oral administration of 600 mg of methylcysteine for 2 months.<BR>Statistically significant decrease was obtained on α<SUB>1</SUB>-acidglycoprotein, IgM and complements, such as hemolytic activity; CH<SUB>50</SUB> and components of the complement system; C<SUB>3</SUB> (β<SUB>1</SUB>A/β<SUB>1</SUB>C), factor Bb (C<SUB>3</SUB> activator) and C<SUB>9</SUB>.<BR>These data are possible to interplete the result of antiinflammation, so L-cysteine and cysteine derivatives may possibly useful as one of anticomplementary drugs.
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