THE STUDY OF BLOOD GROUP FACTORS IN THE RABBIT

概要

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The present study was undertaken in an effort to systematize the knowledge of blood groups in the rabbit through utilization of a large colony of rabbits at the Jackson Memorial Laboratory by Carl Cohen. This report covers the first phase of the work, demonstrating the presence and the classification of blood group antigen of rabbits by using the anti-sera, A, (B), C, D, E, F, H and I respectively, which are prepared by Carl Cohen.The results of the present investigation are as follows:1) The iso-agglutinins were present in the serum of the rabbits tested in the ratio of 36 out of 154 (23.4%). The sera were compared by cross-matching.2) The agglutination titer in the serum of rabbits was very low at room temperature and the serum did not react at 30°C or higher. No hemolysis occurred in any sera.3) The blood grouping could not be used as a basis to determine whether or not given blood types would agglutinate. In some cases agglutination might have been the result of low temperature.4) This is the first investigation conducted in Japan in an attempt to classify the blood groups of rabbits by using the group specific anti-sera prepared by Carl Cohen. In this study the frequency of CF and ACF combination of blood groups was extremely high but the single type of blood was not detected in the present investigation except for F factor.
一般社団法人日本輸血・細胞治療学会の論文