CLINICOPATHOLOGICAL STUDY OF PRIMARY HYPERPARATHYROIDISM
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概要
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From May 1967 to January 1990, 20 patients with a clinical diagnosis of primary hyperparathyroidism (P-HPT) were treated surgically at our department.<BR>In this series, histological types were 16 adenomas (80%), 2 hyperplasia and one carcinoma. There were five men and 15 women, aged from 17 to 69 years (a mean age of 48. 5 years). Abnormal parathyroid gland could not be found intraoperatively in one case.<BR>In the adenoma cases, histologically, 3 cases showed cellular atypism and findings suspicious of capsular invasion which were defined as borderline.<BR>On biochemical data, all cases showed high values for C-PTH and serum level of calcium excluding two cases of normocalcemia.<BR>The equivalent diagnostic value of ultrasound sonography (US), CT scan (CT) and 201T1-99m Tc subtraction in preoperative localization studies revealed values of 100%, 83.3% and 50% respectively. US and CT were thus concluded to be very useful examination for localization of the pathology.<BR>The prognosis showed a very satisfactory outcome excluding one death case of carcinoma.<BR>It is important that P-HPT is diagnosed and treated as early as possible.
- 北関東医学会の論文
北関東医学会 | 論文
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