The application of Clathrate technologies to New Functional preservatives.
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概要
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In development of industrial biocide, formulation technique is becoming important to assure safety. Isothiazolone is an excellent raw material as a general purpose biocide, but has a disadvantage that it is irritative to human skin and requires caution in handling.<BR>To solve these defects, we studied inclusion of isothiazolone into a clathrate compound, and succeeded in greatly reducing the skin-irritative property of isothiazolone without sacrificing the biocide effect.<BR>The host itself has a biocidal effect, so the clathrate gained a synergistic effect in preventing growth of <I>Bacillus sp.</I> in starch. The flowable product developed in this study has reduced skin-irritation, improved compatibility with coating color, without any adverse effect on high-shear viscosity of the coating color.
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