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A 39-year-old female patient, a housewife, with multiple myeloma (IgG, lambda type) succumbed due to massive accumulation of malignant pleural effusion in the right hemithorax. At autopsy, the right pleural cavity was observed to be filled with numerous metastatic myeloma nodules and myeloma cells were demonstrated in the pleural effusion.Cytophotometric DNA measurement of myeloma cells in the pleural effusion was performed. Almost all myeloma cells showed DNA amounts much higher than tetraploid value and two definite distributional modes indicated populations of stemline cells in the higher polyploid DNA range on the DNA frequency-distribution histogram. The cytological pathogenesis was discussed in relation to the appearance of myeloma cells with such polyploid DNA amounts in the pleural effusion.
- 社団法人 日本呼吸器学会の論文
社団法人 日本呼吸器学会 | 論文
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- Investigation of the remaining lung function after lung surgery using ventilation and perfusion scintigraphy.
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- Pleural contact pressure and factors maintaining lung expansion