A Case of Bullous Pemphigoid Presenting with Oral Symptom at the First Examination

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We report a case of immunohistologically diagnosed bullous pemphigoid that first occurred in the oral cavity, and cicatricial pemphigoid was suspected. The patient was a 66-year-old male, who noticed intra-oral haphalgesia approximately 8 months earlier, and received treatment at a local dentist 4 months later; however, no improvement was observed. The paient had previously been infected with viral hepatitis type C, and he has received treatment for diabetes. Although no symptoms were observed in the skin or eyes, intra-oral ulceration was observed in the labio-buccal gingival margin, and in part of the attached gingiva in 6+6, and along the palatal gingival margin in the maxilla. Furthermore, in 7, ulceration ranging from the buccal gingiva to the alveolar crest and the palatal gingiva, as well as erosion in the buccal mucosa, were observed. Because cicatricial pemphigoid was suspected from the clinical symptoms, biopsy was performed, and the lesion was diagnosed as bullous pemphigoid that first occurred in the oral cavity. The intra-oral symptoms improved after treatment with intra-oral irrigation and washing the mouth in our department, and administration of tetracycline and nicotinic acid amide by the department of dermatology.
日本口腔内科学会の論文