Clinical Analysis of Sjögren Syndrome

概要

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Thirty-two cases of Sjögren syndrome were clinically analyzed. The patients were 1 male and 31 females and the average age was 56.4 years. Dry mouth was observed in about 90% of the patients. Saliva secretion was decreased within 3ml and 10ml in more than 80% of the patients under physiological and stimulated conditions, respectively. Parotid gland sialography revealed the characteristic findings in 16 of 29 cases (55.2%) and lip biopsy revealed the infiltration of lymphocytes in 22 of 30 cases (73.3%). Salivary gland scintigraphy revealed moderate or severe impairment of accumulation at the parotid gland in 13 cases (40.6%) and at the submandibular gland in 21 cases (65.6%), respectively. Keratoconjunctivitis sicca was found in 18 cases (56.3%). Serologically, anti-SS-A and anti-SS-B antibodies were positive in 20 cases (62.5%) and 8 cases (25.0%), respectively.
日本口腔内科学会の論文