Research on the effective use of colostrum. Specifically on the effect of colostrum with the administration of enterotoxigenic escherichia coli Vaccine and its efficiency after deep freezing and dehydration.:Specifically on the effect of colostrum with th
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After three Holstein or Jersey cows had one or two injections of enterotoxigenic Escherichia coli vaccine administered under the cervical region one or two months before delivery, the effect of the cows' colostrum on different calves was examined. With the result of this study, the efficiency of deep freezing dehydrated colostrum was sludied.<BR>As a result of these studies, the titer of agglutinin against the adhesive factors K99, FY, and 31A in the colostrum of cows that were vaccinated was 32.0±27.7, 1, 194.7±782.1, and 1, 194.7±782.1 times that of the titer of agglutinin against these same factors in cows that were not vaccinated.<BR>In spite of varying numbers of administrations for each cow, the increase of agglutinin (P<0.01) was significant compared with that of the cows without vaccine administration. However, each titer of agglutinin at the milking after 12-24 hours showed a 70-80% decrease. When this colostrum at the first milking was put into a dehydrated deep freeze and then administered to calves, the amount of γ-globulin in the serum was absorbed into the blood of the 3 liter administration group so fast that it reached the peak ratio of 0.89 g/dl 24 hours after administration. However, the peaks of the 1 liter administration group and the 2 liter administration group were low, about 0.7g/dl, and the time to reach the peaks was delayed for four days.<BR>On the other hand, although the changes in the titer of agglutinin showed that the increase of the titer of agglutinin was recognized in proportion to the dose of deep frozen dehydrated colostrum, FY showed the highest amount of agglutinin in the 1 liter administration group: Moreover, the delay of absorbing agglutinin into the blood was recognized in FY and 3IA. Each case, however, showed that the titer of agglutinin absorbed into the blood with the deep frozen dehydrated colostrurm was higher than than that of the agglutinin with the colostrum that was not deep frozen dehydrated. These results showed that the deep frozen dehydrated colostrrum with vaccine was very effective in preserving colostrum and in protecting newly born calves against infection.
- 日本家畜臨床学会の論文
日本家畜臨床学会 | 論文
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