Induction of abortion in cows with Prostaglandin F2.ALPHA.-analogue or with Dexamethasone.
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Induction of abortion in cows with Prostaglandin F2α-analogue or with Dexamethasone.<BR>Yohji Ohnami, M. Sasaki, M. Kikuchi (School of Vet. Med. Anim. Sci., Kitasato Univ.)<BR>When plostaglandinF2α-analogue (PGF2α-A) was administered at a dose of 0.8-2.4mg into 29 cows in the 2nd-8th month of pregnancy, an abortion was induced in all of the 16 cows in the 2nd to the 4th month of pregnancy, 5 of the 6 in the 5th month, but not in the cows in the 6-8th month. When administered with dexamethasone (Dx) at 30mg, an abortion was induced in neither of the two cows that were less than 5 months pregnant. However, abortions were induced in 2 of the 3 in the 5th month, one in the 6th month, and both in the 8-9th month of pregnancy experienced an abortion or went into premature labor.<BR>Retained placenta was not found in the cows up to the 4th month of pregnancy, but it was observed in all of the cows that were pregnant more than 5 months. In respect to the occurrence of retaind placenta, there was no difference between PGF2α-A and Dx administration. The mean blood progesterone (P) level in the cows which underwent an abortion were 0.9 ng/ml or less at the time around the abortion, although the level was 5.7 ng/ml on the day of PGF2α-A administration. The P level of the cows in which an abortion was induced by Dx, was 6.8 ng/ml on the day of drug administration and reached 1.0 ng/ml or less more than 3 days later. These results indicate that PGF2α-A is markedly effective in inducing an abortion in cows up to the 4th month of pregnancy and Dx is effective in cows pregnant 6 months or more.
- 日本家畜臨床学会の論文
日本家畜臨床学会 | 論文
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