A treatment trial of Cephapirin intramammal injection for lactating stage use in cattle with mastitis.
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概要
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A treatment trial of cephapirin injection (KP-10) for lactating stage was done in 55 cattle with mastitis (76 tests) at South-west Kaminoyama area, Yamagata Prefecture. KP-10 was given intramammaly at a dose of 250mg to a test for 3 days (s.i.d). In con-trol, combination of benzylpenicillin and dihydrostreptomycin sulfate was used. Clinical findings before and after treatment, modifoed CMT and microbial culture were com-pared between treated and control groups. Based on the clinical findings, and numbers of bacteria and cell, 85.4 and 64.3% was judged as effectively treated in KP-10 and con-trol groups, respectivery (P<0.05). Basaed on the udder fingings, milk and modified CMT, 72.9 and 57.1% was effective in the two groups, respevtively. Based on the improvment in cell number by modified CMT (agglutination) was 97.9 and 75.0% in the two groups, respecivery (P<0.01). Comparing numbers of the causal bacteria at pre-and post in administration, 83.3 and 57.1% of the cattle became negative in both groups (P<0.02). KP-10 was effective in 89.5% of the cattle with Staphylococcus sp . and 75.0% of those with Streptocoochu sp., respectively. In control, effectivess was noted in 88.9% for Staphylococcus sp. and 62.5% for Streptococcus sp., respectively. The causal isolated from the milk at pre-administration were highly sennsitiive to KP-10, but some strains or variants were weakly sensitive to penicillin and streptomycin. These results cleary re-vealed that KP-10 was effective to lactating stage mastitis in cattle.
- 日本家畜臨床学会の論文
日本家畜臨床学会 | 論文
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