Plasma vitamin A, D and E concentrations on "Hyena Disease" in cattle.

概要

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Hyena Disease occurred in ten calves aged 12 to 15 months old in 3 farms (A, B and C) in the Iwate Prefecture on March 1991. Nine calves in Farms A and B had been orally administrated a vitamin AD3E premix, but it was unknown whether or not the premix had been given to one calf in Farm C.<BR>The main clinical findings in the cases were marked underdeveloped hindquarters, distinct sloping dorsa and abnormal gait. Plasma 25-hydroxyvitamin D concentration decreased remarkably in all of the animals, but the plasma 1, 25-dihydroxyvitamin D concentration showed normal range or decreased. Other biochemical examinations did not show a remarkable change. In the pathological examination of No.2, an autopsy revealed a shortening of the femur, tibia, humerus and vertebra.<BR>These results suggested that Hyena Disease may be directly related to hypervitaminosis of Aor/and D3 in the early stage after birth, and indirectly to vitamin D deficiency in the growth stage.
日本家畜臨床学会の論文