The Progress of a Case of Localized Amyloidosis of the Larynx.

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There has been no report of the progress of a localized amyloidosis of the larynx in Japan. We report on a 54-year old female with laryngeal amyloidosis who had a relapse and developed another lesion seven years after her initial treatment. At first, she had localized amyloidosis, complaining dyspnea and hoarsness, and received a laryngofissure. Seven years later, she complained of a sense of discomfort. The relapse in the larynx was discovered and lesions in the nasopharymc, epiglottis, arytenoid and trachea were discovered with amyloid deposits. We performed a tracheotomy and removed the tumor, after which the subjective symptoms disappeared. Systemic amyloidosis and multiple myeloma were excluded by serum and urine protein electrophoresis, electrocardiogram and bone marrow biopsy. A long-term follow-up is required, because the disease can recur up to several years after the initial treatment.
特定非営利活動法人日本気管食道科学会の論文