:Part 2. Effects of Various Nutritional Conditions on Distribution and Fecal Excretion of Cholesterol in the Cholesterol-fed Rats
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概要
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The purpose of the present study was to determine the effects of cornstarch replacement with sucrose in a diet containing 1% cholesterol and 0.25% sodium cholate on the cholesterol metabolism in rats with various dietary conditions.The kinds of carbohydrates produced no difference in growth rates, but sucrose diet resulted in a higher level of serum and liver cholesterol than did starch. Dry weight and cholesterol contents of feces excreted by animal for 4 or 8 experimental days were decreased by sucrose diets. Interactions between the dietary carbohydrates and fats were observed in the fecal output of cholesterol; the animals fed on the sucrose diet with soybean oil excreted more cholesterol in feces than ones fed the lard-sucrose diet. Conversely, in the starch diet, the lard diet stimulated more fecal excretion of cholesterol than the soybean one.In the different kind of dietary fats, a marked elevation of serum cholesterol level was caused in the animals placed on the lard diets. Soybean oil stimulated the increased cholesterol content of large intestine and more fecal excretion of cholesterol.The replacement of dietary carbohydrate with konjac flour remarkably depressed the rise in serum and liver cholesterol levels caused by cholesterol and cholate intake. The animals fed konjac flour accumulated more cholesterol in the contents of large intestine, which should be excreted to feces. Concomitant feeding of konjac flour with soybean oil gave the various effects on the cholesterol lowering rate in the serum and liver than single feeding of them.The substantial change of the concentration and amount of carcass cholesterol in the rats fed various diets was not found in a series of experiments.
- 特定非営利活動法人 日本栄養改善学会の論文
特定非営利活動法人 日本栄養改善学会 | 論文
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