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This paper was planned to study the antioxidative action of vitamin E in the tissues of rats fed on diets with different protein lvels. The animals were fed basal diets with or without supplementation of vitamin E (d, l-α-tocopherol) for 4 weeks. The peroxidation of several tissues was examined by the thiobarbituric acid (TBA) assay.Results obtained were as follows.The values of TBA in the liver, kidneys and muscle were significantly higher in the vitamin E deficient groups than in the vitamin E supplemented groups.Statistical difference of TBA values in the liver between vitamin E supplemented groups and vitamin E dificient groups was relatively higher than those in the kidneys and muscle. When the dietaryprotein level was graded at 1.0, 1.5, 2.0 and 3.0% nitrogen levels, TBA values in the liver showed no difference among the four protein groups.Some differences in the liver fatty acid pattern were observed between the vitamin E supplemented groups and the vitamin E deficient groups, i.e., the proportion of palmitic acid of the supplemented groups was significantly lower than that of the deficient groups. But, the proportion of oleic acid of the supplemented groups was significantly higher than that of the vitamin E deficient groups.Cholesterol in plasma and liver, and the total liver lipids were not significantly different among the vitamin E supplemented groups. It was suggested that vitamin E prevented lipid peroxidation in vivo.
- 特定非営利活動法人 日本栄養改善学会の論文
特定非営利活動法人 日本栄養改善学会 | 論文
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