Study for Stresses of Surgical Operation and Electroshock with respect to Urinary Catecholamine Excretion

概要

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It is necessary for the study of nutrition under stress to clarify the hormonal control caused by the stressing factor. Adrenomedullary hormone is known to be the most important hormone to control the metabolism and physiological state under acute stresses. In this experiment, we studied about the electroshock therapy and surgical operation in relation to the urinary catecholamine excretion. The marked increase in epinephrine and norepinephrine excretion was observed immediately after electroshock or surgical operation. Injection of pentothal (anesthetic) and/or inderal (sympathetic β blocking agent), however, resulted in the depression of the increased amount of norepinephrine. While, in the operation, norepinephrine was shown to be very variable in each case. Therefore, it was suggested that the release of norepinephrine was affected by the sensitivity of nervous system to the stressing factor. On the other hand, the release of epinephrine was not changed by the anesthetic or sympathetic blocking agent, and also the change of its daily excretion for a week after operation was similar to each case. These results suggested that release of epinephrine was not significantly affected by the sensitivity of nervous system.
特定非営利活動法人日本栄養改善学会の論文