Changes of Hematocrit, Hemoglobin, Serum Protein Levels and Red Blood Cell Counts Before and After Stroke
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概要
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Changes of hematocrit, hemoglobin, serum protein levels and red blood cell counts were studied in 21 subjects with cerebral infarction and in 16 subjects with intracranial hemorrhage over 60 years of age. Of 16 cases with intracranial hemorrhage 12 were hypertensive intracerebral or intracerebellar bleeding, and 4 subarachnoid hemorrhage. In all cases the diagnosis was confirmed by autopsy. Patients with disseminated intravascular coagulation and cerebral embolism were excluded from this study. Measurements were repeatedly performed within several days before stroke, at the onset of stroke and the succeeding periods.In cerebral infarction the mean value of hematocrit immediately after stroke was significantly higher than that of several days before stroke. The mean values of hemoglobin, serum protein levels and red blood cell counts measured immediately after cerebral infarction were also significantly higher than those within 4 days before stroke. In cases of intracranial hemorrhage, however, there were no significant differences in hematocrit, hemoglobin, serum protein levels and red blood cell counts between the measurements before and after stroke. It is suggested that rapid rise in hematocrit level may play a role in the development of cerebral infarction. There were no significant differences in the mean values of hematocrit between the cases with cerebral infarction and age-matched control subjects.The mean values of hematocrit, hemoglobin levels and red blood cell counts in cases of cerebral infarction were found to be significantly higher than those in cases of intracranial hemorrhage before or immediately after stroke, while there were no significant differences in serum protein levels between the cases of cerebral infarction and intracranial hemorrhage.Both in cerebral infarction and intracranial hemorrhage, the values of hematocrit, hemoglobin levels and red blood cell counts showed the tendency of increasing for about one week after stroke, thereafter decreased; whereas the serum protein levels decreased rapidly after stroke. It is concluded that an elevation of hematocrit will be one of risk factors in cerebral infarction.
- 社団法人 日本老年医学会の論文