Study on Prediction of Cerebrovascular Accidents in Long-term Treated Hyertensive Patients:Multivariate Regression Analysis on the Risk Factors to Cerebrovascular Seizures
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概要
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From 1963, we are treating hypertensive patients at The Jyohoku Hospital Clinic and a mass medical examination for circulation diseases are carried out on them in every summer. To study the significance of examination findings, such as blood pressure, albuminuria, glucosuria, electro-cardiogram, etc. to the cerebrovascular accidents, we selected 277 patients who have been undergoing regular treatment and thoroughly examined over 5 years.The hypertension of these patients was essential and the age of these were ranged from 50 to 74 years.During the course of this study, cerebrovascular accidents occured in 29 cases of these patients. (22 cases of infarction, 7cases of hemorrhage.) 41 of 277 patients have died. 16 patients died from cerebrovascular accidents. (40 per cent of all death) 9 patients died from ischmic heart diseases, (22 per cent of all death) Similarly 9 patients died from malignant tumors. (22per cent of all death)The analysis of relationship between the findings and the accidents were carried out by the multivariate regression method, because these examination findings are related to each other. The calculation was carried out by computer. The conclusion is following:1) By the estimation of partial correlation coefficients, the factors which had significant positive relationship with cerebral infarctions are following:i) Glucosuria, ST-T depression, and arteriosclerotic changes of the eye ground at the first period of the course of this study.ii) The fluctuation of blood pressure occurred often over the blood pressure at the first period.iii) 180 and/or 100mmHg and more blood pressure during the course of the study.But the obesity (over Broca's index+20%) had significant negative relationship with the accidents.2) In the same way, cerebral hemorrhages are related significantly to initial proteinuria and hyertensivec changes of the eye ground at the first period of this study, and 180 and/or 100mmHg and more during the course.Conseqently, supervising of the complications which had presented initially at the first period of the course of this study is important, in addition to the need for the continuous close treatment of hypertension.
- 社団法人 日本老年医学会の論文