MR Image-guided Focused Ultrasound Surgery
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概要
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Focused ultrasound surgery (FUS) is a completely noninvasive, focal thermal ablation method. Various clinical applications of ultrasound-guided FUS have been investigated over the last five decades. However, three inherent challenges limited the clinical efficacy of FUS until recently : imprecise localization, inability to monitor temperature elevation at the focal point, and difficulty evaluating the procedure's success during or immediately after treatment. Recent advances in magnetic resonance (MR) imaging have resolved these problems. Pretreatment MR images enable precise target definition and treatment planning. Temperature-sensitive phase-difference MR imaging can monitor the focal point and measure tissue temperature elevation in real time, ensuring delivery of a therapeutic dose. Posttreatment gadolinium-enhanced MR images provide immediate assessment of the treatment's success. In this article we review the principles, therapeutic methods, and clinical applications of MR image-guided FUS.
- 日本ハイパーサーミア学会の論文
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